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RNF8/UBC13 ubiquitin signaling suppresses synapse formation in the mammalian brain
Although ubiquitin ligases have been implicated in autism, their roles and mechanisms in brain development remain incompletely understood. Here, we report that in vivo knockdown or conditional knockout of the autism-linked ubiquitin ligase RNF8 or associated ubiquitin-conjugating enzyme UBC13 in rod...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5668370/ https://ncbi.nlm.nih.gov/pubmed/29097665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01333-6 |
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