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Ubc13: the Lys63 ubiquitin chain building machine

Ubc13 is an ubiquitin E2 conjugating enzyme that participates with many different E3 ligases to form lysine 63-linked (Lys63) ubiquitin chains that are critical to signaling in inflammatory and DNA damage response pathways. Recent studies have suggested Ubc13 as a potential therapeutic target for in...

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Publicat a:Oncotarget
Autors principals: Hodge, Curtis D., Spyracopoulos, Leo, Glover, J. N. Mark
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5325457/
https://ncbi.nlm.nih.gov/pubmed/27486774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10948
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