Tumor PDCD1LG2 (PD-L2) expression and the lymphocytic reaction to colorectal cancer

Expression of the immune-checkpoint ligand CD274 (programmed cell death 1 ligand 1, PD-L1, from gene CD274) contributes to suppression of antitumor T cell–mediated immune response in various tumor types. However, the role of PDCD1LG2 (PD-L2, CD273, from gene PDCD1LG2) in the tumor microenvironment r...

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Veröffentlicht in:Cancer Immunol Res
Hauptverfasser: Masugi, Yohei, Nishihara, Reiko, Hamada, Tsuyoshi, Song, Mingyang, da Silva, Annacarolina, Kosumi, Keisuke, Gu, Mancang, Shi, Yan, Li, Wanwan, Liu, Li, Nevo, Daniel, Inamura, Kentaro, Cao, Yin, Liao, Xiaoyun, Nosho, Katsuhiko, Chan, Andrew T., Giannakis, Marios, Bass, Adam J., Hodi, F. Stephen, Freeman, Gordon J., Rodig, Scott J., Fuchs, Charles S., Qian, Zhi Rong, Nowak, Jonathan A., Ogino, Shuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668177/
https://ncbi.nlm.nih.gov/pubmed/29038297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-17-0122
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