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Access to enantioenriched 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter by Pd-catalyzed asymmetric intermolecular Heck reaction

A palladium-catalyzed intermolecular asymmetric Heck reaction with dihydrofurans with a trisubstituted double bond is reported. The use of two different chiral ligands provides access to valuable 2,3- and 2,5-dihydrofurans with a fully substituted C2 stereocenter with high levels of regio- and enant...

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Vydáno v:Chem Sci
Hlavní autoři: Borrajo-Calleja, Gustavo M., Bizet, Vincent, Bürgi, Thomas, Mazet, Clément
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667573/
https://ncbi.nlm.nih.gov/pubmed/29142715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01460c
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