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An Evolution-Based Approach to De Novo Protein Design

EvoDesign is a computational algorithm that allows the rapid creation of new protein sequences that are compatible with specific protein structures. As such, it can be used to optimize protein stability, to resculpt the protein surface to eliminate undesired protein-protein interactions, and to opti...

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Pubblicato in:Methods Mol Biol
Autori principali: Brender, Jeffrey R., Shultis, David, Khattak, Naureen Aslam, Zhang, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5667548/
https://ncbi.nlm.nih.gov/pubmed/27914055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-6637-0_12
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