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An Evolution-Based Approach to De Novo Protein Design and Case Study on Mycobacterium tuberculosis
Computational protein design is a reverse procedure of protein folding and structure prediction, where constructing structures from evolutionarily related proteins has been demonstrated to be the most reliable method for protein 3-dimensional structure prediction. Following this spirit, we developed...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812052/ https://ncbi.nlm.nih.gov/pubmed/24204234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003298 |
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