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Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn‐mediated local protein translation
The cause of protein accumulation in neurodegenerative disease is incompletely understood. In Alzheimer's disease (AD), the axonally enriched protein Tau forms hyperphosphorylated aggregates in the somatodendritic domain. Consequently, a process of subcellular relocalization driven by Tau phosp...
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| Gepubliceerd in: | EMBO J |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley and Sons Inc.
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666608/ https://ncbi.nlm.nih.gov/pubmed/28864542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797724 |
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