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Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn

The protein tyrosine kinase Pyk2 is encoded by PTK2B, a novel Alzheimer’s disease (AD) susceptibility variant, with the PTK2B risk allele being associated with increased mRNA levels, suggestive of increased Pyk2 levels. However, the role of Pyk2, a member of the focal adhesion kinase (FAK) family, i...

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Bibliographic Details
Published in:J Alzheimers Dis
Main Authors: Li, Chuanzhou, Götz, Jürgen
Format: Artigo
Language:Inglês
Published: IOS Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004899/
https://ncbi.nlm.nih.gov/pubmed/29782321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-180054
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