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Structural Principles in the Development of Cyclic Peptidic Enzyme Inhibitors
This review summarizes our studies in the development of small cyclic peptides for specifically modulating enzyme activity. Serine proteases share highly similar active sites but perform diverse physiological and pathological functions. From a phage-display peptide library, we isolated two mono-cycl...
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| Publicado no: | Int J Biol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ivyspring International Publisher
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5666521/ https://ncbi.nlm.nih.gov/pubmed/29104489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.21597 |
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