Oral administration of pyrophosphate inhibits connective tissue calcification

Various disorders including pseudoxanthoma elasticum (PXE) and generalized arterial calcification of infancy (GACI), which are caused by inactivating mutations in ABCC6 and ENPP1, respectively, present with extensive tissue calcification due to reduced plasma pyrophosphate (PPi). However, it has alw...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Dedinszki, Dóra, Szeri, Flóra, Kozák, Eszter, Pomozi, Viola, Tőkési, Natália, Mezei, Tamás Róbert, Merczel, Kinga, Letavernier, Emmanuel, Tang, Ellie, Le Saux, Olivier, Arányi, Tamás, van de Wetering, Koen, Váradi, András
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666306/
https://ncbi.nlm.nih.gov/pubmed/28701330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201707532
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