Functional rescue of ABCC6 deficiency by 4-phenylbutyrate therapy reduces dystrophic calcification in Abcc6(−/−) mice

Soft tissue calcification is associated with aging, common conditions such as diabetes or hypercholesterolemia and with certain genetic disorders. ABCC6 is an efflux transporter primarily expressed in liver facilitating the release of ATP from hepatocytes. Within the liver vasculature, ATP is conver...

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Detaylı Bibliyografya
Yayımlandı:J Invest Dermatol
Asıl Yazarlar: Pomozi, Viola, Brampton, Christopher, Szeri, Flóra, Dedinszki, Dóra, Kozák, Eszter, van de Wetering, Koen, Hopkins, Hi’ilani, Martin, Ludovic, Váradi, András, Le Saux, Olivier
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5326614/
https://ncbi.nlm.nih.gov/pubmed/27826008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jid.2016.10.035
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