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Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice

Soft tissue calcification occurs in several common acquired pathologies, such as diabetes and hypercholesterolemia, or can result from genetic disorders. ABCC6, a transmembrane transporter primarily expressed in liver and kidneys, initiates a molecular pathway inhibiting ectopic calcification. ABCC6...

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Bibliografiske detaljer
Udgivet i:Am J Pathol
Main Authors: Pomozi, Viola, Brampton, Christopher, van de Wetering, Koen, Zoll, Janna, Calio, Bianca, Pham, Kevin, Owens, Jesse B., Marh, Joel, Moisyadi, Stefan, Váradi, András, Martin, Ludovic, Bauer, Carolin, Erdmann, Jeanette, Aherrahrou, Zouhair, Le Saux, Olivier
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455066/
https://ncbi.nlm.nih.gov/pubmed/28416300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.02.009
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