Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice

Soft tissue calcification occurs in several common acquired pathologies, such as diabetes and hypercholesterolemia, or can result from genetic disorders. ABCC6, a transmembrane transporter primarily expressed in liver and kidneys, initiates a molecular pathway inhibiting ectopic calcification. ABCC6...

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Bibliografski detalji
Izdano u:Am J Pathol
Glavni autori: Pomozi, Viola, Brampton, Christopher, van de Wetering, Koen, Zoll, Janna, Calio, Bianca, Pham, Kevin, Owens, Jesse B., Marh, Joel, Moisyadi, Stefan, Váradi, András, Martin, Ludovic, Bauer, Carolin, Erdmann, Jeanette, Aherrahrou, Zouhair, Le Saux, Olivier
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2017
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455066/
https://ncbi.nlm.nih.gov/pubmed/28416300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.02.009
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