Pyrophosphate Supplementation Prevents Chronic and Acute Calcification in ABCC6-Deficient Mice

Soft tissue calcification occurs in several common acquired pathologies, such as diabetes and hypercholesterolemia, or can result from genetic disorders. ABCC6, a transmembrane transporter primarily expressed in liver and kidneys, initiates a molecular pathway inhibiting ectopic calcification. ABCC6...

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Bibliografiska uppgifter
I publikationen:Am J Pathol
Huvudupphovsmän: Pomozi, Viola, Brampton, Christopher, van de Wetering, Koen, Zoll, Janna, Calio, Bianca, Pham, Kevin, Owens, Jesse B., Marh, Joel, Moisyadi, Stefan, Váradi, András, Martin, Ludovic, Bauer, Carolin, Erdmann, Jeanette, Aherrahrou, Zouhair, Le Saux, Olivier
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Investigative Pathology 2017
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5455066/
https://ncbi.nlm.nih.gov/pubmed/28416300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2017.02.009
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