Lipoxygenase‐mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3

In cancer cells the small compounds erastin and RSL3 promote a novel type of cell death called ferroptosis, which requires iron‐dependent accumulation of lipid reactive oxygen species. Here we assessed the contribution of lipid peroxidation activity of lipoxygenases (LOX) to ferroptosis in oncogenic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Shintoku, Ryosuke, Takigawa, Yuta, Yamada, Keiichi, Kubota, Chisato, Yoshimoto, Yuhei, Takeuchi, Toshiyuki, Koshiishi, Ichiro, Torii, Seiji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2017
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666033/
https://ncbi.nlm.nih.gov/pubmed/28837253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13380
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg