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Dynamic regulation of EZH2 from HPSc to hepatocyte-like cell fate

Currently, drug metabolization and toxicity studies rely on the use of primary human hepatocytes and hepatoma cell lines, which both have conceivable limitations. Human pluripotent stem cell (hPSC)—derived hepatocyte-like cells (HLCs) are an alternative and valuable source of hepatocytes that can ov...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pistoni, Mariaelena, Helsen, Nicky, Vanhove, Jolien, Boon, Ruben, Xu, Zhuofei, Ordovas, Laura, Verfaillie, Catherine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665677/
https://ncbi.nlm.nih.gov/pubmed/29091973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186884
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