H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro

Although pluripotent stem cells can be differentiated into the hepatocyte lineages, such cells retain an immature phenotype. As the chromatin state of regulatory regions controls spatiotemporal gene expression during development, we evaluated changes in epigenetic histone marks in lineage-specific g...

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Publicat a:Stem Cell Reports
Autors principals: Vanhove, Jolien, Pistoni, Mariaelena, Welters, Marc, Eggermont, Kristel, Vanslembrouck, Veerle, Helsen, Nicky, Boon, Ruben, Najimi, Mustapha, Sokal, Etienne, Collas, Philippe, Voncken, J. Willem, Verfaillie, Catherine M.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982990/
https://ncbi.nlm.nih.gov/pubmed/27477635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.06.013
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