Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers. During their 3–45 s lifetimes, the ESCRT-III...

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Veröffentlicht in:eLife
Hauptverfasser: Adell, Manuel Alonso Y, Migliano, Simona M, Upadhyayula, Srigokul, Bykov, Yury S, Sprenger, Simon, Pakdel, Mehrshad, Vogel, Georg F, Jih, Gloria, Skillern, Wesley, Behrouzi, Reza, Babst, Markus, Schmidt, Oliver, Hess, Michael W, Briggs, John AG, Kirchhausen, Tomas, Teis, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2017
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665648/
https://ncbi.nlm.nih.gov/pubmed/29019322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31652
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