Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers. During their 3–45 s lifetimes, the ESCRT-III...

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Publicado en:eLife
Main Authors: Adell, Manuel Alonso Y, Migliano, Simona M, Upadhyayula, Srigokul, Bykov, Yury S, Sprenger, Simon, Pakdel, Mehrshad, Vogel, Georg F, Jih, Gloria, Skillern, Wesley, Behrouzi, Reza, Babst, Markus, Schmidt, Oliver, Hess, Michael W, Briggs, John AG, Kirchhausen, Tomas, Teis, David
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665648/
https://ncbi.nlm.nih.gov/pubmed/29019322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31652
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