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Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation
Five endosomal sorting complexes required for transport (ESCRTs) mediate the degradation of ubiquitinated membrane proteins via multivesicular bodies (MVBs) in lysosomes. ESCRT-0, -I, and –II interact with cargo on endosomes. ESCRT-II also initiates the assembly of a ringlike ESCRT-III filament cons...
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| Huvudupphovsmän: | , , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
The Rockefeller University Press
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987140/ https://ncbi.nlm.nih.gov/pubmed/24711499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310114 |
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