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Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

Five endosomal sorting complexes required for transport (ESCRTs) mediate the degradation of ubiquitinated membrane proteins via multivesicular bodies (MVBs) in lysosomes. ESCRT-0, -I, and –II interact with cargo on endosomes. ESCRT-II also initiates the assembly of a ringlike ESCRT-III filament cons...

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Bibliografski detalji
Glavni autori: Adell, Manuel Alonso Y, Vogel, Georg F., Pakdel, Mehrshad, Müller, Martin, Lindner, Herbert, Hess, Michael W., Teis, David
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987140/
https://ncbi.nlm.nih.gov/pubmed/24711499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310114
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