Coordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formation

Five endosomal sorting complexes required for transport (ESCRTs) mediate the degradation of ubiquitinated membrane proteins via multivesicular bodies (MVBs) in lysosomes. ESCRT-0, -I, and –II interact with cargo on endosomes. ESCRT-II also initiates the assembly of a ringlike ESCRT-III filament cons...

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Bibliografiska uppgifter
Huvudupphovsmän: Adell, Manuel Alonso Y, Vogel, Georg F., Pakdel, Mehrshad, Müller, Martin, Lindner, Herbert, Hess, Michael W., Teis, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2014
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987140/
https://ncbi.nlm.nih.gov/pubmed/24711499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201310114
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