Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding

The ESCRT machinery mediates reverse membrane scission. By quantitative fluorescence lattice light-sheet microscopy, we have shown that ESCRT-III subunits polymerize rapidly on yeast endosomes, together with the recruitment of at least two Vps4 hexamers. During their 3–45 s lifetimes, the ESCRT-III...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Adell, Manuel Alonso Y, Migliano, Simona M, Upadhyayula, Srigokul, Bykov, Yury S, Sprenger, Simon, Pakdel, Mehrshad, Vogel, Georg F, Jih, Gloria, Skillern, Wesley, Behrouzi, Reza, Babst, Markus, Schmidt, Oliver, Hess, Michael W, Briggs, John AG, Kirchhausen, Tomas, Teis, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2017
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665648/
https://ncbi.nlm.nih.gov/pubmed/29019322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.31652
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