PD-1 blockade augments anti-neuroblastoma immune response induced by anti-GD(2) antibody ch14.18/CHO

Immunotherapy with anti-GD(2) antibody (Ab) ch14.18/CHO is effective for treatment of high-risk neuroblastoma (NB) patients and is mainly based on GD(2)-specific Ab-dependent cellular cytotoxicity (ADCC). Strategies to further enhance the efficacy are important and currently explored in prospective...

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Bibliographische Detailangaben
Veröffentlicht in:Oncoimmunology
Hauptverfasser: Siebert, Nikolai, Zumpe, Maxi, Jüttner, Madlen, Troschke-Meurer, Sascha, Lode, Holger N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665083/
https://ncbi.nlm.nih.gov/pubmed/29123953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1343775
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