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Functional Bioassays for Immune Monitoring of High-Risk Neuroblastoma Patients Treated with ch14.18/CHO Anti-GD(2) Antibody

Effective treatment of high-risk neuroblastoma (NB) remains a major challenge in pediatric oncology. Human/mouse chimeric monoclonal anti-GD(2) antibody (mAb) ch14.18 is emerging as a treatment option to improve outcome. After establishing a production process in Chinese hamster ovary (CHO) cells, c...

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Detalhes bibliográficos
Main Authors: Siebert, Nikolai, Seidel, Diana, Eger, Christin, Jüttner, Madlen, Lode, Holger N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167242/
https://ncbi.nlm.nih.gov/pubmed/25226154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107692
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