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A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells
Mesenchymalization is a cellular and molecular program in which epithelial cells progressively lose their well-differentiated phenotype and adopt mesenchymal characteristics. Tumor mesenchymalization occurs during the progression of cancer to metastatic disease, and is also associated with resistanc...
Shranjeno v:
izdano v: | Oncoimmunology |
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Main Authors: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Taylor & Francis
2017
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5665067/ https://ncbi.nlm.nih.gov/pubmed/29123964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1349589 |
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