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A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells

Mesenchymalization is a cellular and molecular program in which epithelial cells progressively lose their well-differentiated phenotype and adopt mesenchymal characteristics. Tumor mesenchymalization occurs during the progression of cancer to metastatic disease, and is also associated with resistanc...

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Bibliografske podrobnosti
izdano v:Oncoimmunology
Main Authors: David, Justin M., Dominguez, Charli, McCampbell, Kristen K., Gulley, James L., Schlom, Jeffrey, Palena, Claudia
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665067/
https://ncbi.nlm.nih.gov/pubmed/29123964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1349589
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