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Analyses of functions of an anti-PD-L1/TGFβR2 bispecific fusion protein (M7824)
M7824 (MSB0011359C) is a novel first-in-class bifunctional fusion protein consisting of a fully human IgG1 anti-PD-L1 monoclonal antibody (with structural similarities to avelumab) linked to the extracellular domain of two TGFβ receptor 2 (TGFβR2) molecules serving as a TGFβ Trap. Avelumab has demon...
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| Publicado en: | Oncotarget |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5650414/ https://ncbi.nlm.nih.gov/pubmed/29088859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20680 |
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