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Neutralization of IL-8 decreases tumor PMN-MDSCs and reduces mesenchymalization of claudin-low triple-negative breast cancer

The complex signaling networks of the tumor microenvironment that facilitate tumor growth and progression toward metastatic disease are becoming a focus of potential therapeutic options. The chemokine IL-8 is overexpressed in multiple cancer types, including triple-negative breast cancer (TNBC), whe...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Dominguez, Charli, McCampbell, Kristen K., David, Justin M., Palena, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752275/
https://ncbi.nlm.nih.gov/pubmed/29093275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.94296
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