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IL-8 signaling is involved in resistance of lung carcinoma cells to erlotinib
A signaling pathway that is frequently deregulated in human carcinomas and has been explored as a therapeutic target involves the activation of the epidermal growth factor receptor (EGFR). Inhibition of EGFR via the small molecule inhibitors erlotinib and gefitinib commonly results in tumor resistan...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173114/ https://ncbi.nlm.nih.gov/pubmed/27248176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9662 |
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