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Recent insights into PERK-dependent signaling from the stressed endoplasmic reticulum

The unfolded protein response (UPR) is an evolutionarily conserved stress response to intra- and extracellular conditions that disrupt endoplasmic reticulum (ER) protein-folding capacity. The UPR is engaged by a variety of disease conditions, including most cancers as well as both metabolic and neur...

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Bibliographische Detailangaben
Veröffentlicht in:F1000Res
Hauptverfasser: McQuiston, Alexander, Diehl, J Alan
Format: Artigo
Sprache:Inglês
Veröffentlicht: F1000Research 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664976/
https://ncbi.nlm.nih.gov/pubmed/29152224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.12138.1
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