Mutator genomes decay, despite sustained fitness gains, in a long-term experiment with bacteria

Understanding the extreme variation among bacterial genomes remains an unsolved challenge in evolutionary biology, despite long-standing debate about the relative importance of natural selection, mutation, and random drift. A potentially important confounding factor is the variation in mutation rate...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Couce, Alejandro, Caudwell, Larissa Viraphong, Feinauer, Christoph, Hindré, Thomas, Feugeas, Jean-Paul, Weigt, Martin, Lenski, Richard E., Schneider, Dominique, Tenaillon, Olivier
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
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PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664506/
https://ncbi.nlm.nih.gov/pubmed/29073099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705887114
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