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Insertion-sequence-mediated mutations both promote and constrain evolvability during a long-term experiment with bacteria

Insertion sequences (IS) are ubiquitous bacterial mobile genetic elements, and the mutations they cause can be deleterious, neutral, or beneficial. The long-term dynamics of IS elements and their effects on bacteria are poorly understood, including whether they are primarily genomic parasites or imp...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Consuegra, Jessika, Gaffé, Joël, Lenski, Richard E., Hindré, Thomas, Barrick, Jeffrey E., Tenaillon, Olivier, Schneider, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7881107/
https://ncbi.nlm.nih.gov/pubmed/33579917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21210-7
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