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Promiscuous restriction is a cellular defense strategy that confers fitness advantage to bacteria

Most bacterial genomes harbor restriction–modification systems, encoding a REase and its cognate MTase. On attack by a foreign DNA, the REase recognizes it as nonself and subjects it to restriction. Should REases be highly specific for targeting the invading foreign DNA? It is often considered to be...

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Auteurs principaux: Vasu, Kommireddy, Nagamalleswari, Easa, Nagaraja, Valakunja
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356625/
https://ncbi.nlm.nih.gov/pubmed/22509013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1119226109
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