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Evolution of sequence specificity in a restriction endonuclease by a point mutation
Restriction endonucleases (REases) protect bacteria from invading foreign DNAs and are endowed with exquisite sequence specificity. REases have originated from the ancestral proteins and evolved new sequence specificities by genetic recombination, gene duplication, replication slippage, and transpos...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492507/ https://ncbi.nlm.nih.gov/pubmed/18647833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804974105 |
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