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Evolution of sequence specificity in a restriction endonuclease by a point mutation
Restriction endonucleases (REases) protect bacteria from invading foreign DNAs and are endowed with exquisite sequence specificity. REases have originated from the ancestral proteins and evolved new sequence specificities by genetic recombination, gene duplication, replication slippage, and transpos...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2492507/ https://ncbi.nlm.nih.gov/pubmed/18647833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804974105 |
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