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Type II restriction endonuclease R.KpnI is a member of the HNH nuclease superfamily

The restriction endonuclease (REase) R.KpnI is an orthodox Type IIP enzyme, which binds to DNA in the absence of metal ions and cleaves the DNA sequence 5′-GGTAC^C-3′ in the presence of Mg(2+) as shown generating 3′ four base overhangs. Bioinformatics analysis reveals that R.KpnI contains a ββα-Me-f...

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Detalhes bibliográficos
Main Authors: Saravanan, Matheshwaran, Bujnicki, Janusz M., Cymerman, Iwona A., Rao, Desirazu N., Nagaraja, Valakunja
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC534630/
https://ncbi.nlm.nih.gov/pubmed/15562004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh951
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