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PrimPol is required for replication reinitiation after mtDNA damage

Eukaryotic PrimPol is a recently discovered DNA-dependent DNA primase and translesion synthesis DNA polymerase found in the nucleus and mitochondria. Although PrimPol has been shown to be required for repriming of stalled replication forks in the nucleus, its role in mitochondria has remained unreso...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Torregrosa-Muñumer, Rubén, Forslund, Josefin M. E., Goffart, Steffi, Pfeiffer, Annika, Stojkovič, Gorazd, Carvalho, Gustavo, Al-Furoukh, Natalie, Blanco, Luis, Wanrooij, Sjoerd, Pohjoismäki, Jaakko L. O.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664498/
https://ncbi.nlm.nih.gov/pubmed/29073063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705367114
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