PrimPol is required for replication reinitiation after mtDNA damage

Eukaryotic PrimPol is a recently discovered DNA-dependent DNA primase and translesion synthesis DNA polymerase found in the nucleus and mitochondria. Although PrimPol has been shown to be required for repriming of stalled replication forks in the nucleus, its role in mitochondria has remained unreso...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Torregrosa-Muñumer, Rubén, Forslund, Josefin M. E., Goffart, Steffi, Pfeiffer, Annika, Stojkovič, Gorazd, Carvalho, Gustavo, Al-Furoukh, Natalie, Blanco, Luis, Wanrooij, Sjoerd, Pohjoismäki, Jaakko L. O.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664498/
https://ncbi.nlm.nih.gov/pubmed/29073063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705367114
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