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Optimization of the expression, purification and polymerase activity reaction conditions of recombinant human PrimPol
Human PrimPol is a DNA primase/polymerase involved in DNA damage tolerance and prevents nuclear genome instability. PrimPol is also localized to the mitochondria, but its precise function in mitochondrial DNA maintenance has remained elusive. PrimPol works both as a translesion (TLS) polymerase and...
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| Gepubliceerd in: | PLoS One |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5597260/ https://ncbi.nlm.nih.gov/pubmed/28902865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184489 |
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