The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes

BACKGROUND: All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the a...

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Publicat a:Genome Biol
Autors principals: Rissland, Olivia S., Subtelny, Alexander O., Wang, Miranda, Lugowski, Andrew, Nicholson, Beth, Laver, John D., Sidhu, Sachdev S., Smibert, Craig A., Lipshitz, Howard D., Bartel, David P.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664449/
https://ncbi.nlm.nih.gov/pubmed/29089021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1330-z
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