The influence of microRNAs and poly(A) tail length on endogenous mRNA–protein complexes

BACKGROUND: All mRNAs are bound in vivo by proteins to form mRNA–protein complexes (mRNPs), but changes in the composition of mRNPs during posttranscriptional regulation remain largely unexplored. Here, we have analyzed, on a transcriptome-wide scale, how microRNA-mediated repression modulates the a...

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Bibliographic Details
Published in:Genome Biol
Main Authors: Rissland, Olivia S., Subtelny, Alexander O., Wang, Miranda, Lugowski, Andrew, Nicholson, Beth, Laver, John D., Sidhu, Sachdev S., Smibert, Craig A., Lipshitz, Howard D., Bartel, David P.
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664449/
https://ncbi.nlm.nih.gov/pubmed/29089021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1330-z
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