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DRUID: a pipeline for transcriptome-wide measurements of mRNA stability

Control of messenger RNA (mRNA) stability is an important aspect of gene regulation. The gold standard for measuring mRNA stability transcriptome-wide uses metabolic labeling, biochemical isolation of labeled RNA populations, and high-throughput sequencing. However, difficult normalization procedure...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Lugowski, Andrew, Nicholson, Beth, Rissland, Olivia S.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900561/
https://ncbi.nlm.nih.gov/pubmed/29438994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.062877.117
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