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Coding regions affect mRNA stability in human cells
A new paradigm has emerged that coding regions can regulate mRNA stability in model organisms. Here, due to differences in cognate tRNA abundance, synonymous codons are translated at different speeds, and slow codons then stimulate mRNA decay. To ask if this phenomenon also occurs in humans, we isol...
Gardado en:
| Publicado en: | RNA |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Cold Spring Harbor Laboratory Press
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859850/ https://ncbi.nlm.nih.gov/pubmed/31527111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073239.119 |
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