Lanean...

Coding regions affect mRNA stability in human cells

A new paradigm has emerged that coding regions can regulate mRNA stability in model organisms. Here, due to differences in cognate tRNA abundance, synonymous codons are translated at different speeds, and slow codons then stimulate mRNA decay. To ask if this phenomenon also occurs in humans, we isol...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA
Egile Nagusiak: Narula, Ashrut, Ellis, James, Taliaferro, J. Matthew, Rissland, Olivia S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859850/
https://ncbi.nlm.nih.gov/pubmed/31527111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073239.119
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!