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Exploring the Multiligand Binding Specificity of Saposin B Reveals Two Binding Sites
[Image: see text] Saposin B (SapB) is a human lysosomal protein, critical for the degradation of O-sulfogalactosylceramide (sulfatide). SapB binds sulfatide and presents it to the active site of the enzyme arylsulfatase A. Deficiency of SapB leads to fatal activator-deficient metachromatic leukodyst...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2017
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5664142/ https://ncbi.nlm.nih.gov/pubmed/29104953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01334 |
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