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The lysosomal protein saposin B binds chloroquine
Chloroquine has been widely used in the treatment of malaria since the 1950’s. CQ is also becoming an important therapeutic compound for the treatment of auto-immune disorders and has shown activity as an anti-cancer agent. The full extent of CQ pharmacology in humans is still unclear. Herein, we de...
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| Publicado no: | ChemMedChem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558615/ https://ncbi.nlm.nih.gov/pubmed/26616259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500494 |
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