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The lysosomal protein saposin B binds chloroquine

Chloroquine has been widely used in the treatment of malaria since the 1950’s. CQ is also becoming an important therapeutic compound for the treatment of auto-immune disorders and has shown activity as an anti-cancer agent. The full extent of CQ pharmacology in humans is still unclear. Herein, we de...

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Bibliografski detalji
Izdano u:ChemMedChem
Glavni autori: Huta, B. P., Mehlenbacher, M. R., Nie, Y., Lai, X-L., Zubieta, C., Bou-Abdallah, F., Doyle, R. P.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558615/
https://ncbi.nlm.nih.gov/pubmed/26616259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500494
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