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Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b

TRIP8b, an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels, alters both the cell surface expression and cyclic nucleotide dependence of these channels. However, the mechanism by which TRIP8b exerts these dual effects is still poorly understood. In addition...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Bankston, John R., DeBerg, Hannah A., Stoll, Stefan, Zagotta, William N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663879/
https://ncbi.nlm.nih.gov/pubmed/28864772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800722
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