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Mechanism for the inhibition of the cAMP dependence of HCN ion channels by the auxiliary subunit TRIP8b

TRIP8b, an accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) ion channels, alters both the cell surface expression and cyclic nucleotide dependence of these channels. However, the mechanism by which TRIP8b exerts these dual effects is still poorly understood. In addition...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Bankston, John R., DeBerg, Hannah A., Stoll, Stefan, Zagotta, William N.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663879/
https://ncbi.nlm.nih.gov/pubmed/28864772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.800722
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