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Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation

The molecular pathogenesis of human lung cancer has not been completely clarified. Here, we reported that UBE2L3, a member of the ubiquitin-conjugating enzymes (E2s), were overexpressed in non-small-cell lung cancer (NSCLC) tissues compared with the non-tumor tissues. High expression of UBE2L3 was c...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ma, Xingjie, Zhao, Junjie, Yang, Fan, Liu, Haitao, Qi, Weibo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663587/
https://ncbi.nlm.nih.gov/pubmed/29137415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20449
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