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Ubiquitin conjugating enzyme E2 L3 promoted tumor growth of NSCLC through accelerating p27kip1 ubiquitination and degradation

The molecular pathogenesis of human lung cancer has not been completely clarified. Here, we reported that UBE2L3, a member of the ubiquitin-conjugating enzymes (E2s), were overexpressed in non-small-cell lung cancer (NSCLC) tissues compared with the non-tumor tissues. High expression of UBE2L3 was c...

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Foilsithe in:Oncotarget
Main Authors: Ma, Xingjie, Zhao, Junjie, Yang, Fan, Liu, Haitao, Qi, Weibo
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663587/
https://ncbi.nlm.nih.gov/pubmed/29137415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20449
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