TGFBR-IDH1-Cav1 axis promotes TGF-β signalling in cancer-associated fibroblast

TGF-β signalling plays an important role in fibroblasts activation and tumour progression. Here, we report that the TGFBR-IDH1-Cav1 axis promotes TGF- β signalling in fibroblasts. Our data demonstrated that IDH1 was downregulated by TGF-β signalling in fibroblasts, and downregulation of IDH1 increas...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Hou, Xiaodan, Zhang, Jieying, Wang, Yongbin, Xiong, Wujun, Mi, Jun
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663568/
https://ncbi.nlm.nih.gov/pubmed/29137396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20861
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