Glucocorticoids Recruit Tgfbr3 and Smad1 to Shift Transforming Growth Factor-β Signaling from the Tgfbr1/Smad2/3 Axis to the Acvrl1/Smad1 Axis in Lung Fibroblasts

Glucocorticoids represent the mainstay therapy for many lung diseases, providing outstanding management of asthma but performing surprisingly poorly in patients with acute respiratory distress syndrome, chronic obstructive pulmonary disease, lung fibrosis, and blunted lung development associated wit...

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Detalhes bibliográficos
Main Authors: Schwartze, Julian T., Becker, Simone, Sakkas, Elpidoforos, Wujak, Łukasz A., Niess, Gero, Usemann, Jakob, Reichenberger, Frank, Herold, Susanne, Vadász, István, Mayer, Konstantin, Seeger, Werner, Morty, Rory E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916529/
https://ncbi.nlm.nih.gov/pubmed/24347165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.541052
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