Activated spleen tyrosine kinase promotes malignant progression of oral squamous cell carcinoma via mTOR/S6 signaling pathway in an ERK1/2-independent manner

Spleen tyrosine kinase (SYK), a non-receptor cytoplasmic tyrosine enzyme, is well known for its ability in certain pathways through immune receptors. Recently, SYK role in cancer has been widely studied. SYK plays a dual role as a tumor suppressor and tumor promoter. Nevertheless, its role in oral s...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gao, Pan, Qiao, Xianghe, Sun, Haibin, Huang, Yi, Lin, Jie, Li, Longjiang, Wang, Xiaoyi, Li, Chunjie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663563/
https://ncbi.nlm.nih.gov/pubmed/29137391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19911
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