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The mTOR Pathway in Hepatic Malignancies

The mechanistic/mammalian target of rapamycin (mTOR) pathway plays a critical role in cellular metabolism, growth and proliferation, and has been evaluated as a target for therapy in various malignancies. The mTOR pathway is a major tumor-initiating pathway in hepatocellular carcinoma, with upregula...

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Detalhes bibliográficos
Main Authors: Bhat, Mamatha, Sonenberg, Nahum, Gores, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3688698/
https://ncbi.nlm.nih.gov/pubmed/23408390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26323
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