Yüklüyor......
Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements
[Image: see text] Efforts to develop inhibitors, activators, and effectors of biological reactions using small molecule libraries are often hampered by interference compounds, artifacts, and false positives that permeate the pool of initial hits. Here, we report the discovery of a promising initial...
Kaydedildi:
| Yayımlandı: | J Med Chem |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical
Society
2017
|
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5663392/ https://ncbi.nlm.nih.gov/pubmed/28933844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b01071 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|